Rp1hl1 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN314991

Rp1l1 - mouse gene knockout kit via CRISPR

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USD 1,290


Availability*
4 Weeks

Size
    • 1 kit

Product images

Specifications

Product Data
Symbol Rp1hl1
Locus ID 271209
Kit Components

KN314991G1, Rp1hl1 gRNA vector 1 in pCas-Guide vector,

KN314991G2, Rp1hl1 gRNA vector 2 in pCas-Guide vector,

KN314991-D, donor vector containing Left and right homologous arms and GFP-puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq BC129887, NM_146246
Synonyms BC031365; BE983540; Dcdc4; Rp1hl1
Summary This gene encodes a member of the doublecortin family. This protein is a retinal-specific protein. It contains two N-terminal doublecortin domains, which can assemble and stabilize axonemal microtubules, but lacks the C-terminal repetitive regions including the 16aa repeat found in human RP1L1. This protein and the RP1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. [provided by RefSeq, Sep 2010].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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