Rp1hl1 Mouse Gene Knockout Kit (CRISPR)
Rp1l1 - mouse gene knockout kit via CRISPRchange donor?
KN314991G1, Rp1hl1 gRNA vector 1 in pCas-Guide vector,
KN314991G2, Rp1hl1 gRNA vector 2 in pCas-Guide vector,
donor vector containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|Synonyms||BC031365; BE983540; Dcdc4; Rp1hl1|
|Summary||This gene encodes a member of the doublecortin family. This protein is a retinal-specific protein. It contains two N-terminal doublecortin domains, which can assemble and stabilize axonemal microtubules, but lacks the C-terminal repetitive regions including the 16aa repeat found in human RP1L1. This protein and the RP1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. [provided by RefSeq, Sep 2010].|
|Gene Expression Resources|
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