Nox1 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN311133

Nox1 - mouse gene knockout kit via CRISPR

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USD 1,290.00


Availability*
4 Weeks

Size
    • 1 kit

Product images

Specifications

Product Data
Symbol Nox1
Locus ID 237038
Kit Components

KN311133G1, Nox1 gRNA vector 1 in pCas-Guide vector,

KN311133G2, Nox1 gRNA vector 2 in pCas-Guide vector,

KN311133-D, donor vector containing Left and right homologous arms and GFP-puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_172203
Synonyms GP91-2; MOX1; NOH-1; NOH1; Nox-1; NOX1a; NOX1alpha
Summary This gene encodes a subunit of the NADPH oxidase enzyme, which is a membrane-bound, multisubunit protein. This complex catalyzes the transfer of electrons from NADPH to molecular oxygen to produce superoxide or hydrogen peroxide and may have a role in antimicrobial killing and cell signaling. This protein binds other subunits in order to produce superoxide. In mouse, deficiency of this enzyme may be associated with changes in blood pressure. [provided by RefSeq, Jun 2013].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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