Nox1 Mouse Gene Knockout Kit (CRISPR)
Nox1 - mouse gene knockout kit via CRISPRchange donor?
KN311133G1, Nox1 gRNA vector 1 in pCas-Guide vector,
KN311133G2, Nox1 gRNA vector 2 in pCas-Guide vector,
donor vector containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|Synonyms||GP91-2; MOX1; NOH-1; NOH1; Nox-1; NOX1a; NOX1alpha|
|Summary||This gene encodes a subunit of the NADPH oxidase enzyme, which is a membrane-bound, multisubunit protein. This complex catalyzes the transfer of electrons from NADPH to molecular oxygen to produce superoxide or hydrogen peroxide and may have a role in antimicrobial killing and cell signaling. This protein binds other subunits in order to produce superoxide. In mouse, deficiency of this enzyme may be associated with changes in blood pressure. [provided by RefSeq, Jun 2013].|
|Gene Expression Resources|
"Nox1" in other Product Lines
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