Frs3 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN306140

Frs3 - mouse gene knockout kit via CRISPR

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USD 1,290


Availability*
4 Weeks

Size
    • 1 kit

Product images

Specifications

Product Data
Symbol Frs3
Locus ID 107971
Kit Components

KN306140G1, Frs3 gRNA vector 1 in pCas-Guide vector,

KN306140G2, Frs3 gRNA vector 2 in pCas-Guide vector,

KN306140-D, donor vector containing Left and right homologous arms and GFP-puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq BC014819, NM_144939
Synonyms 4930417B13Rik; AI449674; Frs2beta; Snt2
Summary Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2. [UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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