Frs3 Mouse Gene Knockout Kit (CRISPR)
Frs3 - mouse gene knockout kit via CRISPRchange donor?
KN306140G1, Frs3 gRNA vector 1 in pCas-Guide vector,
KN306140G2, Frs3 gRNA vector 2 in pCas-Guide vector,
donor vector containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|Synonyms||4930417B13Rik; AI449674; Frs2beta; Snt2|
|Summary||Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2. [UniProtKB/Swiss-Prot Function]|
|Gene Expression Resources|
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