Dnmt3l Mouse Gene Knockout Kit (CRISPR)
Dnmt3l - mouse gene knockout kit via CRISPRchange donor?
KN304725G1, Dnmt3l gRNA vector 1 in pCas-Guide vector,
KN304725G2, Dnmt3l gRNA vector 2 in pCas-Guide vector,
donor vector containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||BC083147, NM_001081695, NM_001284197, NM_001284198, NM_001284199, NM_001284200, NM_019448|
|Summary||CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein that is a catalytically inactive regulatory factor of DNA methyltransferases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015].|
|Gene Expression Resources|
"Dnmt3l" in other Product Lines
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