Dnmt3l Mouse Gene Knockout Kit (CRISPR)

CAT#: KN304725

Dnmt3l - mouse gene knockout kit via CRISPR

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USD 1,290.00


Availability*
4 Weeks

Size
    • 1 kit

Product images

Specifications

Product Data
Symbol Dnmt3l
Locus ID 54427
Kit Components

KN304725G1, Dnmt3l gRNA vector 1 in pCas-Guide vector,

KN304725G2, Dnmt3l gRNA vector 2 in pCas-Guide vector,

KN304725-D, donor vector containing Left and right homologous arms and GFP-puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq BC083147, NM_001081695, NM_001284197, NM_001284198, NM_001284199, NM_001284200, NM_019448
Summary CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein that is a catalytically inactive regulatory factor of DNA methyltransferases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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