AKR1CL2 Human Gene Knockout Kit (CRISPR)
AKR1E2 - human gene knockout kit via CRISPRchange donor?
HDR-mediated knockout kit validation
KN224970G1, AKR1CL2 gRNA vector 1 in pCas-Guide vector
KN224970G2, AKR1CL2 gRNA vector 2 in pCas-Guide vector
donor DNA containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||NM_001040177, NM_001271021, NM_001271025, NM_031436, NR_073125, NR_073126, NR_073127, XM_011519715, XM_011519718, XM_011519719, XM_011519720, XM_011519722, XM_011519724, XM_011519725, XM_011519729, XM_017016743, XM_017016744, XM_017016745, XR_001747220, XR_001747221, XR_001747222, XR_001747223, XR_930518, XR_930519, XR_930520|
|Synonyms||AKR1CL2; AKRDC1; htAKR; hTSP; LoopADR|
|Summary||The protein encoded by this gene is a member of the aldo-keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD(P)H-dependent oxido-reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].|
|Gene Expression Resources|