MEGF8 Human Gene Knockout Kit (CRISPR)
MEGF8 - human gene knockout kit via CRISPRchange donor?
HDR-mediated knockout kit validation
KN224470G1, MEGF8 gRNA vector 1 in pCas-Guide vector
KN224470G2, MEGF8 gRNA vector 2 in pCas-Guide vector
donor DNA containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|Synonyms||C19orf49; CRPT2; EGFL4; SBP1|
|Summary||The protein encoded by this gene is a single-pass type I membrane protein of unknown function that contains several EGF-like domains, Kelch repeats, and PSI domains. Defects in this gene are a cause of Carpenter syndrome 2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]|
|Gene Expression Resources|