C19orf51 Human Gene Knockout Kit (CRISPR)
DNAAF3 - human gene knockout kit via CRISPRchange donor?
HDR-mediated knockout kit validation
KN223043G1, C19orf51 gRNA vector 1 in pCas-Guide vector
KN223043G2, C19orf51 gRNA vector 2 in pCas-Guide vector
donor DNA containing Left and right homologous arms and RFP-BSD functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||BC016843, BC063449, NM_001031802, NM_001256714, NM_001256715, NM_001256716, NM_178837|
|Synonyms||C19orf51; CILD2; DAB1; PCD; PF22|
|Summary||The protein encoded by this gene is required for the assembly of axonemal inner and outer dynein arms and plays a role in assembling dynein complexes for transport into cilia. Defects in this gene are a cause of primary ciliary dyskinesia type 2 (CILD2). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].|
|Gene Expression Resources|