TNFRSF10C Human Gene Knockout Kit (CRISPR)
TNFRSF10C - human gene knockout kit via CRISPRchange donor?
KN221313G1, TNFRSF10C gRNA vector 1 in pCas-Guide vector,
KN221313G2, TNFRSF10C gRNA vector 2 in pCas-Guide vector,
donor vector containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|Synonyms||CD263; DCR1; DCR1-TNFR; LIT; TRAIL-R3; TRAILR3; TRID|
|Summary||Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand. [UniProtKB/Swiss-Prot Function]|
|Gene Expression Resources|
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