SGIP1 Human Gene Knockout Kit (CRISPR)
SGIP1 - human gene knockout kit via CRISPRchange donor?
HDR-mediated knockout kit validation
KN221213G1, SGIP1 gRNA vector 1 in pCas-Guide vector
KN221213G2, SGIP1 gRNA vector 2 in pCas-Guide vector
donor DNA containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||NM_001308203, NM_001350217, NM_001350218, NM_032291, XM_005271264, XM_005271268, XM_005271270, XM_006710961, XM_006710966, XM_006710967, XM_006710969, XM_006710971, XM_006710972, XM_006710973, XM_006710974, XM_011542291, XM_011542292, XM_011542293, XM_017002505, XM_017002506, XM_017002507, XM_017002508, XM_017002509, XM_017002510, XM_017002511, XM_017002512, XM_017002513, XM_017002514, XM_017002515, XM_017002516, XM_017002517, XM_017002518, XM_017002519, XM_017002520, XM_017002521, XM_017002522, XM_017002523, XM_017002524, XM_017002525, XM_017002526, XM_017002527, XM_017002528, XM_017002529, XM_017002530, XM_017002531, XM_017002532, XM_017002533, XM_017002534, XM_017002535, XM_017002536, XM_017002537, XR_001737483|
|Summary||SGIP1 functions as an endocytic protein that affects signaling by receptors in neuronal systems involved in energy homeostasis via its interaction with endophilins (see SH3GL3; MIM 603362) (Trevaskis et al., 2005 [PubMed 15919751] and Uezu et al., 2007 [PubMed 17626015]).[supplied by OMIM, Mar 2008].|
|Gene Expression Resources|