PLA1A Human Gene Knockout Kit (CRISPR)
PLA1A - human gene knockout kit via CRISPRchange donor?
HDR-mediated knockout kit validation
KN219486G1, PLA1A gRNA vector 1 in pCas-Guide vector
KN219486G2, PLA1A gRNA vector 2 in pCas-Guide vector
donor DNA containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||NM_001206960, NM_001206961, NM_001293225, NM_015900, NR_120610, XM_017006572|
|Summary||The protein encoded by this gene is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine in liposomes. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011].|
|Gene Expression Resources|