PTPRG Human Gene Knockout Kit (CRISPR)
PTPRG - human gene knockout kit via CRISPRchange donor?
KN218964G1, PTPRG gRNA vector 1 in pCas-Guide vector,
KN218964G2, PTPRG gRNA vector 2 in pCas-Guide vector,
donor vector containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||NM_002841, XM_005265353, XM_017006961, XM_017006962, XM_017006963, XM_017006964|
|Synonyms||HPTPG; PTPG; R-PTP-GAMMA; RPTPG|
|Summary||The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq, Jul 2008].|
|Gene Expression Resources|
"PTPRG" in other Product Lines
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