HCRT Human Gene Knockout Kit (CRISPR)
HCRT - human gene knockout kit via CRISPRchange donor?
KN217956G1, HCRT gRNA vector 1 in pCas-Guide vector,
KN217956G2, HCRT gRNA vector 2 in pCas-Guide vector,
donor vector containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|Synonyms||NRCLP1; OX; PPOX|
|Summary||This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis. [provided by RefSeq, Jan 2010].|
|Gene Expression Resources|
"HCRT" in other Product Lines
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