KIF21A Human Gene Knockout Kit (CRISPR)
KIF21A - human gene knockout kit via CRISPRchange donor?
HDR-mediated knockout kit validation
KN217610G1, KIF21A gRNA vector 1 in pCas-Guide vector
KN217610G2, KIF21A gRNA vector 2 in pCas-Guide vector
donor DNA containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||AK000059, NM_001173463, NM_001173464, NM_001173465, NM_017641, XM_005269007, XM_005269008, XM_005269009, XM_005269010, XM_005269011, XM_005269012, XM_005269013, XM_005269014, XM_006719493, XM_006719494, XM_011538556, XM_017019607, XM_017019608, XM_017019609, XM_017019610, XM_017019611, XM_040211, XM_040216|
|Synonyms||CFEOM1; FEOM1; FEOM3A|
|Summary||This gene encodes a member of the KIF4 subfamily of kinesin-like motor proteins. The encoded protein is characterized by an N-terminal motor domain a coiled-coil stalk domain and a C-terminal WD-40 repeat domain. This protein may be involved in microtubule dependent transport. Mutations in this gene are the cause of congenital fibrosis of extraocular muscles-1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010].|
|Gene Expression Resources|