APOBEC3D Human Gene Knockout Kit (CRISPR)
APOBEC3D - human gene knockout kit via CRISPRchange donor?
HDR-mediated knockout kit validation
KN216825G1, APOBEC3D gRNA vector 1 in pCas-Guide vector
KN216825G2, APOBEC3D gRNA vector 2 in pCas-Guide vector
donor DNA containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||NM_152426, XM_005261337, XM_017028596, XR_001755169, XR_001755170|
|Synonyms||A3D; APOBEC3DE; APOBEC3E; ARP6|
|Summary||This gene is a member of the cytidine deaminase gene family. It is one of a group of related genes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA. [provided by RefSeq, Jul 2008].|
|Gene Expression Resources|