ATF7 Human Gene Knockout Kit (CRISPR)
ATF7 - human gene knockout kit via CRISPRchange donor?
KN216022G1, ATF7 gRNA vector 1 in pCas-Guide vector,
KN216022G2, ATF7 gRNA vector 2 in pCas-Guide vector,
donor vector containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||NM_001130059, NM_001130060, NM_001206682, NM_001206683, NM_006856, NR_073163, XM_005268587, XM_017018722|
|Summary||Isoform 5 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation. [UniProtKB/Swiss-Prot Function]|
|Gene Expression Resources|
"ATF7" in other Product Lines
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