ATF7 Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Symbol	ATF7
Locus ID	11016
Kit Components	KN216022G1, ATF7 gRNA vector 1 in pCas-Guide vector, KN216022G2, ATF7 gRNA vector 2 in pCas-Guide vector, KN216022-D, donor vector containing Left and right homologous arms and GFP-puro functional cassette. GE100003, scramble sequence in pCas-Guide vector
Disclaimer	The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_001130059, NM_001130060, NM_001206682, NM_001206683, NM_006856, NR_073163, XM_005268587, XM_017018722
Synonyms	ATFA
Summary	Isoform 5 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation. [UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.