SH3PXD2B Human Gene Knockout Kit (CRISPR)

CAT#: KN214270

SH3PXD2B - human gene knockout kit via CRISPR

change donor?


 HDR-mediated knockout kit validation

USD 1,290.00


Availability*
4 Weeks

Size
    • 1 kit

Product images

Specifications

Product Data
Symbol SH3PXD2B
Locus ID 285590
Kit Components

KN214270G1, SH3PXD2B gRNA vector 1 in pCas-Guide vector

KN214270G2, SH3PXD2B gRNA vector 2 in pCas-Guide vector

KN214270-D, donor DNA containing Left and right homologous arms and GFP-puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001017995, NM_001308175, XM_017009351
Synonyms FAD49; FTHS; HOFI; KIAA1295; TKS4; TSK4
Summary This gene encodes an adapter protein that is characterized by a PX domain and four Src homology 3 domains. The encoded protein is required for podosome formation and is involved in cell adhesion and migration of numerous cell types. Mutations in this gene are the cause of Frank-ter Haar syndrome (FTHS), and also Borrone Dermato-Cardio-Skeletal (BDCS) syndrome. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents