SMARCA6 (HELLS) Human Gene Knockout Kit (CRISPR)

CAT#: KN212231RB

HELLS - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: SMARCA6
• Locus ID: 3070
• Components:

  KN212231G1, SMARCA6 gRNA vector 1 in pCas-Guide CRISPR vector

  KN212231G2, SMARCA6 gRNA vector 2 in pCas-Guide CRISPR vector

  KN212231RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001289067, NM_001289068, NM_001289069, NM_001289070, NM_001289071, NM_001289072, NM_001289073, NM_001289074, NM_001289075, NM_018063
• UniProt ID: Q9NRZ9
• Synonyms: LSH; Nbla10143; PASG; SMARCA6
• Summary: This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2014]