PLCH1 Human Gene Knockout Kit (CRISPR)

CAT#: KN210686

PLCH1 - human gene knockout kit via CRISPR

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 HDR-mediated knockout kit validation

USD 1,290.00


Availability*
4 Weeks

Size
    • 1 kit

Product images

Specifications

Product Data
Symbol PLCH1
Locus ID 23007
Kit Components

KN210686G1, PLCH1 gRNA vector 1 in pCas-Guide vector

KN210686G2, PLCH1 gRNA vector 2 in pCas-Guide vector

KN210686-D, donor DNA containing Left and right homologous arms and GFP-puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001130960, NM_001130961, NM_001349250, NM_001349251, NM_001349252, NM_014996, XM_005247238, XM_005247239, XM_011512560, XM_011512561, XM_011512562, XM_011512564, XM_011512565, XM_011512566, XM_011512567, XM_017005923, XM_017005924, XM_017005925, XM_017005926, XM_017005927, XM_017005928, XM_017005929
Synonyms PLCL3; PLCL3
Summary PLCH1 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to generate second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) (Hwang et al., 2005 [PubMed 15702972]).[supplied by OMIM, Jun 2009].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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