CNR1 Human Gene Knockout Kit (CRISPR)
CNR1 - human gene knockout kit via CRISPRchange donor?
KN210397G1, CNR1 gRNA vector 1 in pCas-Guide vector,
KN210397G2, CNR1 gRNA vector 2 in pCas-Guide vector,
donor vector containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||NM_001160226, NM_001160258, NM_001160259, NM_001160260, NM_001840, NM_016083, NM_033181, XM_006715330, XM_011535424, XM_011535425, XM_011535426, XM_011535428, XM_017010238, XM_017010239, XM_017010240|
|Synonyms||CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR|
|Summary||This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009]|
|Gene Expression Resources|
"CNR1" in other Product Lines
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