BRD7 Human Gene Knockout Kit (CRISPR)
BRD7 - human gene knockout kit via CRISPRchange donor?
HDR-mediated knockout kit validation
KN208734G1, BRD7 gRNA vector 1 in pCas-Guide vector
KN208734G2, BRD7 gRNA vector 2 in pCas-Guide vector
donor DNA containing Left and right homologous arms and mBFP-Neo functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||NM_001173984, NM_013263, XM_011523046, XM_011523047, XM_011523048, XM_011523049, XM_011523050, XM_017023179, XM_017023180, XM_017023181, XM_045692, XR_001751896, XR_933289, XR_933290, XR_933291|
|Synonyms||BP75; CELTIX1; NAG4|
|Summary||This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]|
|Gene Expression Resources|