AP3B1 Human Gene Knockout Kit (CRISPR)
AP3B1 - human gene knockout kit via CRISPRchange donor?
KN207124G1, AP3B1 gRNA vector 1 in pCas-Guide vector,
KN207124G2, AP3B1 gRNA vector 2 in pCas-Guide vector,
donor vector containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||NM_001271769, NM_003664, XM_005248618, XM_005248619, XM_017010001|
|Synonyms||ADTB3; ADTB3A; HPS; HPS2; PE|
|Summary||This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012].|
|Gene Expression Resources|
"AP3B1" in other Product Lines
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