CCL22 Human Gene Knockout Kit (CRISPR)

CAT#: KN206578

CCL22 - human gene knockout kit via CRISPR

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USD 1,290


Availability*
4 Weeks

Size
    • 1 kit

Product images

Specifications

Product Data
Symbol CCL22
Locus ID 6367
Kit Components

KN206578G1, CCL22 gRNA vector 1 in pCas-Guide vector,

KN206578G2, CCL22 gRNA vector 2 in pCas-Guide vector,

KN206578-D, donor vector containing Left and right homologous arms and GFP-puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_002990, XM_017023531
Synonyms A-152E5.1; ABCD-1; DC/B-CK; MDC; SCYA22; STCP-1
Summary May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active. [UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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