CCL22 Human Gene Knockout Kit (CRISPR)
CCL22 - human gene knockout kit via CRISPRchange donor?
KN206578G1, CCL22 gRNA vector 1 in pCas-Guide vector,
KN206578G2, CCL22 gRNA vector 2 in pCas-Guide vector,
donor vector containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|Synonyms||A-152E5.1; ABCD-1; DC/B-CK; MDC; SCYA22; STCP-1|
|Summary||May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active. [UniProtKB/Swiss-Prot Function]|
|Gene Expression Resources|
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