TRIP6 Human Gene Knockout Kit (CRISPR)
TRIP6 - human gene knockout kit via CRISPRchange donor?
KN205778G1, TRIP6 gRNA vector 1 in pCas-Guide vector,
KN205778G2, TRIP6 gRNA vector 2 in pCas-Guide vector,
donor vector containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|Synonyms||OIP-1; OIP1; TRIP-6; TRIP6i2; ZRP-1|
|Summary||This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]|
|Gene Expression Resources|
"TRIP6" in other Product Lines
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