CSH2 Human Gene Knockout Kit (CRISPR)

CAT#: KN204739

CSH2 - human gene knockout kit via CRISPR

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USD 1,290.00

4 Weeks

    • 1 kit

Product images


Product Data
Symbol CSH2
Locus ID 1443
Kit Components

KN204739G1, CSH2 gRNA vector 1 in pCas-Guide vector,

KN204739G2, CSH2 gRNA vector 2 in pCas-Guide vector,

KN204739-D, donor vector containing Left and right homologous arms and GFP-puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_020991, NM_022644, NM_022645, NM_022646
Synonyms CS-2; CSB; GHB1; hCS-B; PL
Summary The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, while the ratio of 1 to 2 increases by term. Structural and expression differences provide avenues for developmental regulation and tissue specificity. [provided by RefSeq, Jul 2008].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.