TGFBRAP1 Human Gene Knockout Kit (CRISPR)
TGFBRAP1 - human gene knockout kit via CRISPRchange donor?
KN204476G1, TGFBRAP1 gRNA vector 1 in pCas-Guide vector,
KN204476G2, TGFBRAP1 gRNA vector 2 in pCas-Guide vector,
donor vector containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||NM_001142621, NM_004257, XM_017005339|
|Summary||This gene encodes a protein that binds to transforming growth factor-beta (TGF-beta) receptors and plays a role in TGF-beta signaling. The encoded protein acts as a chaprone in signaling downstream of TGF-beta. It is involved in signal-dependent association with SMAD4. The protein is also a component of mammalian CORVET, a multisubunit tethering protein complex that is involved in fusion of early endosomes. [provided by RefSeq, Jun 2016]|
|Gene Expression Resources|
"TGFBRAP1" in other Product Lines
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