C12orf57 Human Gene Knockout Kit (CRISPR)
C12orf57 - human gene knockout kit via CRISPRchange donor?
HDR-mediated knockout kit validation
KN201441G1, C12orf57 gRNA vector 1 in pCas-Guide vector
KN201441G2, C12orf57 gRNA vector 2 in pCas-Guide vector
donor DNA containing Left and right homologous arms and GFP-puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
|Disclaimer||The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.|
|RefSeq||NM_001301834, NM_001301836, NM_001301837, NM_001301838, NM_138425, NR_126035|
|Summary||This gene is ubiquitously expressed in human tissues. It is required for development of the human corpus callosum. Mutations in this gene are associated with Temtamy syndrome (TEMTYS). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014].|
|Gene Expression Resources|