Mouse Plcg2 activation kit by CRISPRa

CAT#: GA214569

Plcg2 CRISPRa kit - CRISPR gene activation of mouse phospholipase C, gamma 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: Plcg2
• Locus ID: 234779
• Kit Components:

  GA214569G1, Plcg2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA214569G2, Plcg2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA214569G3, Plcg2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_172285
• UniProt ID: Q8CIH5
• Synonyms: PLC-gamma-2; Plcg-2; PLCgamma2
• Summary: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling (By similarity).[UniProtKB/Swiss-Prot Function]