Mouse ACE2 activation kit by CRISPRa (Angiotensin Converting Enzyme 2)

CAT#: GA208393

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Ace2 CRISPRa kit - CRISPR gene activation of mouse angiotensin I converting enzyme (peptidyl-dipeptidase A) 2

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30% off with code “Activation“, ends on April 30th, 2021. View details.

USD 1,290.00

2 Weeks

    • 1 kit

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Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol Ace2
Locus ID 70008
Kit Components

GA208393G1, Ace2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA208393G2, Ace2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA208393G3, Ace2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001130513, NM_027286
Synonyms 2010305L05Rik
Summary Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. May have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19, regulating its trafficking on the cell surface and its activity (PubMed:19185582).[UniProtKB/Swiss-Prot Function]

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68 Mouse Clones
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