Human GPR 139 (GPR139) activation kit by CRISPRa

SKU GA114834

GPR139 CRISPRa kit - CRISPR gene activation of human G protein-coupled receptor 139

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: GPR139
• Locus ID: 124274
• Components:

  GA114834G1, GPR 139 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114834G2, GPR 139 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114834G3, GPR 139 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001002911, NM_001318483
• UniProt ID: Q6DWJ6
• Synonyms: GPRg1; PGR3
• Summary: This gene encodes a member of the rhodopsin family of G-protein-coupled receptors. The encoded protein is almost exclusively expressed in the central nervous system. L-tryptophan and L-phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]