Human BFSP2 activation kit by CRISPRa

CAT#: GA105561

BFSP2 CRISPRa kit - CRISPR gene activation of human beaded filament structural protein 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: BFSP2
• Locus ID: 8419
• Kit Components:

  GA105561G1, BFSP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105561G2, BFSP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105561G3, BFSP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003571
• UniProt ID: Q13515
• Synonyms: CP47; CP49; CTRCT12; LIFL-L; PHAKOSIN
• Summary: More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex. [provided by RefSeq, Jun 2009]