Human VEGFC activation kit by CRISPRa

CAT#: GA105117

VEGFC CRISPRa kit - CRISPR gene activation of human vascular endothelial growth factor C

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: VEGFC
• Locus ID: 7424
• Kit Components:

  GA105117G1, VEGFC gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105117G2, VEGFC gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105117G3, VEGFC gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005429
• UniProt ID: P49767
• Synonyms: Flt4-L; LMPH1D; VRP
• Summary: The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors. [provided by RefSeq, Apr 2014]