Human RNase L (RNASEL) activation kit by CRISPRa

SKU GA104117

RNASEL CRISPRa kit - CRISPR gene activation of human ribonuclease L

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: RNASEL
• Locus ID: 6041
• Components:

  GA104117G1, RNase L gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104117G2, RNase L gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104117G3, RNase L gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_021133
• UniProt ID: Q05823
• Synonyms: PRCA1; RNS4
• Summary: This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele. [provided by RefSeq, Jul 2008]