Human M-CSF (CSF1) activation kit by CRISPRa

CAT#: GA101009

CSF1 CRISPRa kit - CRISPR gene activation of human colony stimulating factor 1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CSF1
• Locus ID: 1435
• Kit Components:

  GA101009G1, M-CSF gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101009G2, M-CSF gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101009G3, M-CSF gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000757, NM_172210, NM_172211, NM_172212
• UniProt ID: P09603
• Synonyms: CSF-1; MCSF
• Summary: The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]