Human 12 Lipoxygenase (ALOX12) activation kit by CRISPRa

CAT#: GA100166

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ALOX12 CRISPRa kit - CRISPR gene activation of human arachidonate 12-lipoxygenase, 12S type



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USD 1,290.00


Availability*
2 Weeks

Size
    • 1 kit

Product images

Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol ALOX12
Locus ID 239
Kit Components

GA100166G1, 12 Lipoxygenase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100166G2, 12 Lipoxygenase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100166G3, 12 Lipoxygenase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000697
Synonyms 12-LOX; 12S-LOX; LOG12
Summary This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on different polyunsaturated fatty acid substrates to generate bioactive lipid mediators including eicosanoids and lipoxins. The encoded enzyme and its reaction products have been shown to regulate platelet function. Elevated expression of this gene has been observed in pancreatic islets derived from human diabetes patients. Allelic variants in this gene may be associated with susceptibility to toxoplasmosis. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]

Other Versions

Other products for "ALOX12"
Frequently bought together (3)
ALOX12 mouse monoclonal antibody, clone OTI1C3 (formerly 1C3)
    • 100 ul

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ALOX12 (Myc-DDK-tagged)-Human arachidonate 12-lipoxygenase (ALOX12)
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USD 420.00


ALOX12 mouse monoclonal antibody, clone OTI5H2 (formerly 5H2)
    • 30 ul

USD 159.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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