Hsd17b11 (NM_001004209) Rat Tagged ORF Clone Lentiviral Particle

CAT#: RR213495L3V

Lenti ORF particles, Hsd17b11 (Myc-DDK-tagged ORF) - Rat hydroxysteroid (17-beta) dehydrogenase 11 (Hsd17b11), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Rat Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Hsd17b11
• Synonyms: Dhrs8
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001004209
• ORF Size: 894 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RR213495).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001004209.1, NP_001004209.1
• RefSeq Size: 1622 bp
• RefSeq ORF: 897 bp
• Locus ID: 289456
• UniProt ID: Q6AYS8
• Cytogenetics: 14p22
• Gene Summary: Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione.[UniProtKB/Swiss-Prot Function]