SERINC5 (NM_001174072) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC230125L1V

Lenti ORF particles, SERINC5 (Myc-DDK tagged) - Human serine incorporator 5 (SERINC5), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: SERINC5
• Synonyms: C5orf12; TPO1
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_001174072
• ORF Size: 1383 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC230125).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001174072.1
• RefSeq ORF: 1386 bp
• Locus ID: 256987
• UniProt ID: Q86VE9
• Cytogenetics: 5q14.1
• Protein Families: Transmembrane
• MW: 51.8 kDa
• Gene Summary: Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm (PubMed:26416733, PubMed:26416734). Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes (By similarity).[UniProtKB/Swiss-Prot Function]