FGD5 (NM_152536) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC229441L1V

Lenti ORF particles, FGD5 (Myc-DDK-tagged)-Human FYVE, RhoGEF and PH domain containing 5 (FGD5), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: FGD5
• Synonyms: ZFYVE23
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_152536
• ORF Size: 4386 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC229441).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_152536.3
• RefSeq ORF: 4389 bp
• Locus ID: 152273
• UniProt ID: Q6ZNL6
• Cytogenetics: 3p25.1
• Domains: RhoGEF, FYVE, PH
• MW: 159.7 kDa
• Gene Summary: Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.[UniProtKB/Swiss-Prot Function]