CHFR (NM_001161347) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC228465L2V

Lenti ORF particles, CHFR (mGFP-tagged) - Human checkpoint with forkhead and ring finger domains (CHFR), transcript variant 5, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: CHFR
• Synonyms: RNF116; RNF196
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_001161347
• ORF Size: 1716 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC228465).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001161347.1, NP_001154819.1
• RefSeq ORF: 1719 bp
• Locus ID: 55743
• UniProt ID: Q96EP1
• Cytogenetics: 12q24.33
• Protein Families: Druggable Genome
• MW: 63.7 kDa
• Gene Summary: This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014]