SVH (ARMC10) (NM_001161013) Human Tagged ORF Clone Lentiviral Particle
SKU
RC228156L3V
Lenti ORF particles, ARMC10 (Myc-DDK-tagged)-Human armadillo repeat containing 10 (ARMC10), transcript variant F, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | SVH |
Synonyms | PNAS-112; PNAS112; PSEC0198; SVH |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC228156).
|
ACCN | NM_001161013 |
ORF Size | 675 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_001161013.2, NP_001154485.1 |
RefSeq Size | 2297 bp |
RefSeq ORF | 678 bp |
Locus ID | 83787 |
UniProt ID | Q8N2F6 |
Cytogenetics | 7q22.1 |
Protein Families | Transmembrane |
MW | 24.8 kDa |
Summary | This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Sep 2011] |
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