SAE1 (NM_016402) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC227950L3V

Lenti ORF particles, SAE1 (Myc-DDK tagged) - Human SUMO1 activating enzyme subunit 1 (SAE1), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: SAE1
• Synonyms: AOS1; FLJ3091; HSPC140; SUA1; UBLE1A
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_016402
• ORF Size: 1038 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC227950).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_016402.1, NP_057486.1
• RefSeq Size: 2538 bp
• RefSeq ORF: 1040 bp
• Locus ID: 10055
• Cytogenetics: 19q13.32
• Protein Pathways: Ubiquitin mediated proteolysis
• MW: 38.4 kDa
• Gene Summary: Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]