Apolipoprotein L 1 (APOL1) (NM_001136541) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC226644L4V

Lenti ORF particles, APOL1 (mGFP-tagged)-Human apolipoprotein L, 1 (APOL1), transcript variant 4, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: APOL1
• Synonyms: APO-L; APOL; APOL-I; FSGS4
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001136541
• ORF Size: 1140 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC226644).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001136541.1, NP_001130013.1
• RefSeq ORF: 1143 bp
• Locus ID: 8542
• UniProt ID: O14791
• Cytogenetics: 22q12.3
• Protein Families: Secreted Protein, Transmembrane
• MW: 42 kDa
• Gene Summary: This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]