Lysosomal acid lipase (LIPA) (NM_001127605) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC225622L3V

Lenti ORF particles, LIPA (Myc-DDK tagged) - Human lipase A, lysosomal acid, cholesterol esterase (LIPA), transcript variant 1, 200ul, >10^7 TU/mL

Product Images

RC225622L3 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC225622L3V particle to overexpress human LIPA-Myc-DDK fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: LIPA
• Synonyms: CESD; LAL
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001127605
• ORF Size: 1197 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC225622).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001127605.1
• RefSeq ORF: 1200 bp
• Locus ID: 3988
• UniProt ID: P38571
• Cytogenetics: 10q23.31
• Protein Families: Druggable Genome
• Protein Pathways: Lysosome, Steroid biosynthesis
• MW: 45.42 kDa
• Gene Summary: This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014]