GAD65 (GAD2) (NM_000818) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC223464L3V

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  • LentiORF®

Lenti ORF particles, GAD2 (Myc-DDK tagged) - Human glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) (GAD2), transcript variant 1, 200ul, >10^7 TU/mL



USD 850.00


Availability*
5 Weeks

Size
    • 200 ul


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Specifications

Product Data
Product Name GAD65 (GAD2) (NM_000818) Human Tagged ORF Clone Lentiviral Particle
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol GAD2
Synonyms GAD65
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_000818
ORF Size 1755 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC223464).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_000818.1, NP_000809.1
RefSeq Size 2824 bp
RefSeq ORF 1758 bp
Locus ID 2572
Cytogenetics 10p12.1
Protein Families Druggable Genome
Protein Pathways Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Butanoate metabolism, Metabolic pathways, Taurine and hypotaurine metabolism, Type I diabetes mellitus
MW 65.4 kDa
Gene Summary This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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