ALDH1A2 (NM_003888) Human Tagged ORF Clone Lentiviral Particle

SKU
RC223250L2V
Lenti ORF particles, ALDH1A2 (mGFP-tagged)-Human aldehyde dehydrogenase 1 family, member A2 (ALDH1A2), transcript variant 1, 200ul, >10^7 TU/mL
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    Expression-ready ORF plasmid in lenti backbone

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$1,032.00
5 Weeks*
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Target Symbol ALDH1A2
Synonyms RALDH(II); RALDH2; RALDH2-T
Vector pLenti-C-mGFP
Mammalian Cell Selection None
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC223250).
ACCN NM_003888
ORF Size 1554 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_003888.2
RefSeq Size 3398 bp
RefSeq ORF 1557 bp
Locus ID 8854
UniProt ID O94788
Cytogenetics 15q21.3
Domains aldedh
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Retinol metabolism
MW 56.5 kDa
Summary This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2011]
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