HTRA1 (NM_002775) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC222362L3V

Lenti ORF particles, HTRA1 (Myc-DDK tagged) - Human HtrA serine peptidase 1 (HTRA1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: HTRA1
• Synonyms: ARMD7; CADASIL2; CARASIL; HtrA; L56; ORF480; PRSS11
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_002775
• ORF Size: 1440 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC222362).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_002775.3
• RefSeq Size: 2133 bp
• RefSeq ORF: 1443 bp
• Locus ID: 5654
• UniProt ID: Q92743
• Cytogenetics: 10q26.13
• Domains: IB, Tryp_SPc, PDZ, kazal
• Protein Families: Druggable Genome, Protease, Secreted Protein
• MW: 51.3 kDa
• Gene Summary: This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008]