OATP2 (SLCO1B1) (NM_006446) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC222130L2V

Lenti ORF particles, SLCO1B1 (mGFP-tagged) - Human solute carrier organic anion transporter family, member 1B1 (SLCO1B1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: OATP2
• Synonyms: HBLRR; LST-1; LST1; OATP-C; OATP1B1; OATP2; OATPC; SLC21A6
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_006446
• ORF Size: 2073 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC222130).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006446.2
• RefSeq Size: 2830 bp
• RefSeq ORF: 2076 bp
• Locus ID: 10599
• UniProt ID: Q9Y6L6
• Cytogenetics: 12p12.1
• Domains: OATP_N, OATP_C
• Protein Families: Druggable Genome, Transmembrane
• MW: 76.3 kDa
• Gene Summary: This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009]