LCLAT1 (NM_182551) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC220664L4V

  • LentiORF®

Lenti ORF particles, LCLAT1 (mGFP-tagged) - Human lysocardiolipin acyltransferase 1 (LCLAT1), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro


Special Offer: Buy this product and get 50% off Lenti Control Particles. Learn More.

USD 1,236.00

2 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol LCLAT1
Synonyms 1AGPAT8; AGPAT8; ALCAT1; HSRG1849; LYCAT; UNQ1849
Mammalian Cell Selection Puromycin
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_182551
ORF Size 1242 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC220664).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_182551.3
RefSeq Size 5077 bp
RefSeq ORF 1245 bp
Locus ID 253558
UniProt ID Q6UWP7
Cytogenetics 2p23.1
Protein Families Transmembrane
Protein Pathways Ether lipid metabolism, Glycerolipid metabolism, Glycerophospholipid metabolism, Limonene and pinene degradation, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism
MW 48.7 kDa
Gene Summary Exhibits acyl-CoA:lysocardiolipin acyltransferase (ALCAT) activity; catalyzes the reacylation of lyso-cardiolipin to cardiolipin (CL), a key step in CL remodeling (By similarity). Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors (By similarity). Also exhibits 1-acyl-sn-glycerol-3-phosphate acyltransferase activity (AGPAT) activity; converts 1-acyl-sn-glycerol-3- phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3- phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed:16620771). Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities (PubMed:19075029). Required for establishment of the hematopoietic and endothelial lineages (By similarity).[UniProtKB/Swiss-Prot Function]

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