Natriuretic Peptide Receptor B (NPR2) (NM_003995) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC220459L2V

Lenti ORF particles, NPR2 (mGFP-tagged) - Human natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) (NPR2), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: Natriuretic Peptide Receptor B
• Synonyms: AMDM; ANPb; ANPRB; ECDM; GC-B; GCB; GUC2B; GUCY2B; NPRB; NPRBi; SNSK
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_003995
• ORF Size: 3141 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC220459).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003995.3
• RefSeq Size: 3447 bp
• RefSeq ORF: 3144 bp
• Locus ID: 4882
• UniProt ID: P20594
• Cytogenetics: 9p13.3
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Purine metabolism, Vascular smooth muscle contraction
• MW: 117.02 kDa
• Gene Summary: This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008]