eRF1 (ETF1) (NM_004730) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC220387L4V

Lenti ORF particles, ETF1 (mGFP-tagged) - Human eukaryotic translation termination factor 1 (ETF1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: eRF1
• Synonyms: D5S1995; ERF; ERF1; RF1; SUP45L1; TB3-1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_004730
• ORF Size: 1311 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC220387).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_004730.1
• RefSeq Size: 3653 bp
• RefSeq ORF: 1314 bp
• Locus ID: 2107
• UniProt ID: P62495
• Cytogenetics: 5q31.2
• Domains: eRF1_1, eRF1_2, eRF1_3
• MW: 48.9 kDa
• Gene Summary: This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X. [provided by RefSeq, Aug 2013]