MADCAM1 (NM_130760) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC219060L1V

Lenti ORF particles, MADCAM1 (Myc-DDK tagged) - Human mucosal vascular addressin cell adhesion molecule 1 (MADCAM1), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: MADCAM1
• Synonyms: MACAM1
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_130760
• ORF Size: 1146 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC219060).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_130760.2
• RefSeq Size: 1546 bp
• RefSeq ORF: 1149 bp
• Locus ID: 8174
• UniProt ID: Q13477
• Cytogenetics: 19p13.3
• Protein Pathways: Cell adhesion molecules (CAMs)
• MW: 38.3 kDa
• Gene Summary: The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]